Compositions and methods for reducing neovascularization. Purified nucleic acid constructs and vectors encoding an anti-angiogenic protein operably linked to a GFAP promoter. Vectors can include at least one hypoxia regulated element, enhancer element and silencer element. Gene therapy methods for reducing, delaying or preventing neovascularization based on the nucleic acid constructs and vectors.

 
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< Pancreatic polypeptide family motifs, polypeptides and methods comprising the same

< Transgenic mouse with a targeted deletion of Elovl4 gene

> Pharmaceutical compositions and medical treatments comprising notch ligand proteins

> RNA interference mediated inhibition of matrix metalloproteinase 13 (MMP13) gene expression using short interfering nucleic acid (siNA)
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