Disclosed are compounds of formula:
##STR1##
and pharmaceutically acceptable salts and esters thereof, useful in treating
and/or preventing Alzheimer's disease and other similar diseases, wherein RN,
RC, R1, R2 and R20 are defined herein.
These compounds include inhibitors of the beta-secretase enzyme that are useful
in the treatment of Alzheimer's disease and other diseases characterized by deposition
of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical
compositions and methods of treatment to reduce A beta peptide formation.
