A method for the facile and inexpensive inducible expression of heterologous
genes
has been discovered. The yhcS regulator gene has been found to be inducible by
aromatic carboxylic acids and to alter the expression of operons in the LysR gene
family, including the yhcRQP operon, common in enteric bacteria. Heterologous nucleic
acid molecules placed under the control of yhcs responsive promoters may be overexpressed
in response to the presence of inexpensive aromatic carboxylic acids.