Proteins derived from the product of tumor suppressor gene p53 and having enhanced functions for therapeutical use are disclosed. The proteins advantageously have enhanced tumour suppressor and programmed cell death inducer functions, particularly in proliferative disease contexts where wild-type p53 protein is inactivated. Nucleic acids coding for such molecules, vectors containing same, and therapeutical use thereof, particularly in gene therapy, are also disclosed.

 
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< Mammalian proteinases; oxidoreductases; related reagents

< Genetic engineering of plants through manipulation of lignin biosynthesis

> C3 -methylene hydrogen phosphonate oligomers and related compounds

> Farnesyl pyrophosphate synthase protein, nucleic acid and promoter region thereof

~ 00201