Synthetic processes are provided wherein oligomeric compounds are prepared having phosphodiester, phosphorothioate, phosphorodithioate, or other covalent linkages. The oligomers have substantially reduced exocyclic adducts deriving from acrylonitrile or related contaminants.

 
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> Modulation of diacylglycerol acyltransferase 2 expression

> Novel 2'-C-methyl nucleoside derivatives

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