The present invention relates to a novel follistatin-3 protein which is a member
of the family of inhibin-related proteins. In particular, isolated nucleic acid
molecules are provided encoding the human follistatin-3 protein. Follistatin-3
polypeptides are also provided as are vectors, host cells and recombinant methods
for producing the same. The invention further relates to screening methods for
identifying agonists and antagonists of follistatin-3 activity. Also provided are
diagnostic methods for detecting reproductive system-related disorders and disorders
of the regulation of cell growth and differentiation and therapeutic methods for
treating reproductive system-related disorders and disorders of the regulation
of cell growth and differentiation.
