The invention relates to novel collagen peptides that are modified by grafting
free or substitued thiol functions carried by mercaptoamine radicals. The aim of
the invention is to provide thiol collagens that can be cross-linked in a sufficient
and controlled manner by forming S-S bridges and which are biocompatible. This
is achieved by means of the inventive thiol collagens which are characterized in
that the mercaptoamine radicals are identical to or different from each other and
are exclusively grafted on the aspartic and glutamic acids of the collagen chain
by amide bonds. The invention also relates to a method for the production of said
thiol and cross-linkable collagens. The novel modified cross-linkable and/or cross-linked
collagens can be used as biomaterials.
