Triarylimidazole derivatives as cytokine inhibitors

   
   

Compounds of formula (I) or a pharmaceutically acceptable salt thereof: ##STR1##

    • wherein R1, R2 and R3 are various substituent groups; and
    • one of X1 and X2 is N or CR, and the other is NR or CHR wherein R is hydrogen, OH, C1-6alkyl, or C3-7cycloalkyl; or when one of X1 and X2 is N or CR then the other may be S or O;
    • and their use as pharmaceuticals.
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