A cardiac rhythm management system detects hypotension, such as by using thoracic
impedance to detect a fluid shift away from the thorax. In response to an episode
of detected hypotension, it increases a pacing rate response factor mapping a metabolic
need to an indicated pacing rate provided by the system. The metabolic need is
indicated by an accelerometer, a respiration sensor, or other metabolic need sensor
indicating a subject's need for adjusting cardiac output.
