Gene delivery system and methods of use

   
   

A recombinant replication competent retrovirus for gene deliver and gene therapy is provided. The recombinant retrovirus has a heterologous nucleic acid sequence, a sequence encoding a cell- or tissue-specific ligand or a sequence for transcriptional targeting, or a combination of both a cell- or tissue-specific ligand and a cell- or tissue-specific transcriptional targeting sequence.

 
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< Screening assays for agonists and antagonists of receptor activator of NF-B

< Filamentary means for introducing agents into tissue of a living host

> Biocompatible material composition adaptable to diverse therapeutic indications

> Lineage restricted glial precursors from the central nervous system

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