This invention relates to a breakthrough method for pre-sensitizing cancer prior
to a therapeutic treatment such as chemotherapy, radiation therapy or immuno-therapy
and a novel cytokine mixture used in the method thereof. The cytokine mixture is
a serum-free and mitogen-free mixture comprised of specific ratios of cytokines
such as IL-1, TNF-, IFN- and GM-CSF to Interleukin 2 (IL-2),
which is effective in inducing cancerous cells to enter a proliferative cell cycle
phase thereby increasing their vulnerability to chemotherapy, radiation therapy
and immuno-therapy. One such novel cytokine mixture is Multikine, which can
be used alone or in combination with other drugs for the treatment of cancer thereby
increasing the success of cancer treatment and the disease free survival of cancer patients.
