There is provided an orally-administrable formulation for the controlled release
or stable storage of a granulated isoflavone-enriched fraction or mixture of such
fractions, comprising at least one granulated isoflavone-enriched fraction and
at least one carrier, diluent or excipient therefor. Preferably, the formulation
is characterized in that the total in vitro dissolution time of said formulation
required for release of 75% of the active ingredients available from the formulation
is between about 4 and about 18 hours, as determined by the U.S.P. XXIII paddle
method at a paddle speed of 75 rpm, using simulated intestinal fluid without the
digestive enzymes normally found in intestinal fluid, at pH 6.8, and a temperature
of 37 C. A process for the preparation of such a formulation is also provided.
