Recombinantly produced L1 major capsid proteins which mimic conformational
naturalizing epitopes on human and animal papilloma virions including canine and
equine papilloma virions are provided. These recombinant proteins are useful as
vaccines for conferring protection against papillomavirus infection. Antibodies
to the recombinant protein are also provided. Such antibodies are useful in the
diagnosis and treatment of viral infection.