Methods of controlling calcium intake and phosphate metabolism and metabolic
acidosis in patients suffering from renal failure and associated hyperphosphatemia
or patients predisposed to development of a hyperphosphatemic condition are provided.
The method in accordance with this invention comprises administering to a patient
a calcium glutarate compound. Therapeutic benefit can be realized in accordance
with such method by administering the compound orally to a patient to increase
available calcium and contact and bind with ingested phosphate in the patient's
digestive tract, and thereby prevent its intestinal absorption.