Process for 8-carboxamido-2,6-methano-3-benzazocines

   
   

8-Substituted-2,6-methano-3-benzazocines of general structure I in which A is CH2OH, CH2NH2, NHSO2CH3, ##STR1##

and Y is O, S or

NOH are useful as analgesics, anti-diarrheal agents, anticonvulsants, antitussives and anti-addiction medications. ##STR2##

8-Carboxamides, thiocarboxamides, hydroxyamidines and formamides are preferred.

 
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