Antimicrobial dihydrothiazine and dihydrothiopyran oxazolidinones

   
   

The present invention provides a compound of formula I ##STR1##

or a pharmaceutically acceptable salt thereof wherein A is a structure i, ii, iii, or iv ##STR2##

X is CR7; Y is S(O)n, S(NR8), or S(NR8)(O); Z is NHC(O)R1, NHC(S)R1, NR-het1, O-het1, S-het1, or -het2; and n is independently 0, 1, or 2. The compounds of formula I are useful as antimicrobials against a number of human and veterinary pathogens.

 
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