The use of a compound comprising formula (I), or a salt, ester, amide or
prodrug thereof in the treatment of obesity and related disorders. The
invention also relates to novel compounds within formula (I), to
processes for preparing them and pharmaceutical compositions containing
them. In formula (I): A is an optionally substituted thienyl moiety, Y is
O, S, or NR.sup.2, R.sup.1 is a branched or unbranched alkyl (optionally
interrupted by one or more oxygen atoms), alkenyl, alkynyl, cycloalkyl,
cycloalkenyl, aryl, arylalkyl, reduced arylalkyl, arylalkenyl,
heteroaryl, heteroarylalkyl, heteroarylalkenyl, reduced aryl, reduced
heteroaryl, reduced heteroarylalkyl or a substituted derivative of any of
the foregoing groups and R.sup.2 is hydrogen or a group as defined for
R.sup.1. 1
