Statine derivatives for the treatment of Alzheimer's disease

   
   

The present invention relates to compounds of formula (I): ##STR1## useful in treating Alzheimer's disease and other similar diseases. These compounds include inhibitors of the beta-secretase enzyme that are useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal. The compounds of the invention are useful in pharmaceutical compositions and methods of treatment to reduce A beta peptide formation.

A invenção atual relaciona-se aos compostos da fórmula (i): ## do ## STR1 útil em outras doenças similares de Alzheimer de tratamento na doença e. Estes compostos incluem os inibidores do enzyme beta-secretase-secretase que são úteis no tratamento da doença de Alzheimer e em outras doenças caracterizadas pelo deposition do peptide beta de A em um mamífero. Os compostos da invenção são úteis em composições e em métodos de tratamento pharmaceutical reduzir a formação beta do peptide de A.

 
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> Long-acting oxytocin analogues for the treatment and prevention of breast cancer and psychiatric disorders

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