Method for the delivery of a biologically active agent

   
   

A method of manufacturing a stable nanosuspension for delivery of a biologically active agent into the bloodstream of a subject is disclosed. A microfluidizable mixture is initially formed and processed via a microfluidization process to form the stable nanosuspension, which may be administered via the buccal mucosa or other suitable routes of administration. This product demonstrates increased bioavailability, enhanced period of onset, and enhanced stability for a controlled-release product.

Un método de fabricar un nanosuspension estable para la entrega de un agente biológico activo en la circulación sanguínea de un tema se divulga. Una mezcla microfluidizable se forma y se procesa inicialmente vía un proceso del microfluidization para formar el nanosuspension estable, que se puede administrar vía la mucosa bucal u otras rutas de la administración convenientes. Este producto demuestra biodisponibilidad creciente, realzado período del inicio, y la estabilidad realzada para controlado-lanza el producto.

 
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