Methods for producing highly phosphorylated lysosomal hydrolases

   
   

The present invention provides highly phosphorylated lysosomal hydrolases, methods of modifying lysosomal hydrolases with the lysosomal targeting pathway enzymes GlcNAc-phosphotransferase and/or phosphodiester .alpha.-GlcNAcase.

Присытствыющий вымысел обеспечивает высоки phosphorylated lysosomal гидролазы, методы дорабатывать lysosomal гидролазы с lysosomal пристреливая энзимами GlcNAc-phosphotransferase pathway and/or alpha.-GlcNAcase phosphodiester.

 
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