Novel glycosylsulfotransferases (GST-4.alpha., GST-4.beta., and GST-6) and
polypeptides related thereto, as well as nucleic acid compositions
encoding the same, are provided. The subject polypeptides and nucleic acid
compositions find use in a variety of applications, including various
diagnostic and therapeutic agent screening applications. Also provided are
methods of inhibiting selectin mediated binding events and methods of
treating disease conditions associated therewith, particularly by
administering an inhibitor of at least one of GST-4.alpha., GST-4.beta.,
and GST-6.
