Gene encoding brain-specific membrane protein

   
   

A novel gene apparently encoding a transmembrane glycoprotein has been successfully isolated by constructing a cDNA library of 4 kb or above in size from mRNA expressed in human adult brain and analyzing the structures of cDNAs contained within said library by the shotgun method. The novel gene shows brain-specific expression and the protein encoded by said gene has a typical PDZ protein binding motif.

Un gene de la novela que codificaba al parecer una glicoproteína del transmembrane ha sido aislado con éxito construyendo una biblioteca de la DNA de 4 KB o arriba de tamaño del mRNA expresado en cerebro humano del adulto y analizando las estructuras de DNAS contenido dentro de la biblioteca dicha por el método de la escopeta. La expresión cerebro-especi'fica de las demostraciones del gene de la novela y la proteína codificadas por el gene dicho tiene un adorno obligatorio de la proteína típica de PDZ.

 
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