Thioketals and thioethers for inhibiting the expression of VCAM-1

   
   

Thioketals and thioethers are provided that inhibit the expression of VCAM-1, and which can be used in the treatment of VCAM-1 mediated diseases including inflammatory disorders, cardiovascular diseases, occular diseases, autoimmune diseases, neurological disorders, and cancer. The compounds also can be used to treat hyperlipidemia and/or hypercholesterolemia.

Thioketals en thioethers worden verstrekt die de uitdrukking van vcam-1 remmen, en die in de behandeling van vcam-1 bemiddelde ziekten met inbegrip van ontstekingswanorde, cardiovasculaire ziekten, occular ziekten, auto-immune ziekten, neurologische wanorde, en kanker kunnen worden gebruikt. De samenstellingen kunnen ook worden gebruikt om hyperlipidemia en/of hypercholesterolemia te behandelen.

 
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