Methods and interferon deficient substrates for the propagation of viruses

   
   

The present invention relates, to novel methods and substrates for the propagation of viruses. The invention relates to IFN-deficient substrates and methods for propagating viruses in these unconventional substrates. In particular, the invention relates to methods of propagating viruses in immature embryonated eggs, preferably six- to nine-day-old chicken eggs. The methods of the invention are particularly attractive for growing viruses suitable for use in vaccine and pharmaceutical formulations.

A invenção atual relaciona-se, aos métodos da novela e às carcaças para a propagação dos vírus. A invenção relaciona-se às carcaças IFN-iFN-deficient e aos métodos para propagar vírus nestas carcaças unconventional. No detalhe, a invenção relaciona-se aos métodos de propagar vírus em immature embryonated os ovos, preferivelmente seis aos ovos nove-dia-velhos da galinha. Os métodos da invenção são particularmente atrativos para os vírus crescentes apropriados para o uso em formulations vacinais e pharmaceutical.

 
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