The present invention provides non-steroidal compounds of Formula I,
including prodrugs and pharmaceutically acceptable salts thereof, which
are selective modulators (e.g., agonists, partial agonists and
antagonists) of a steroid receptor, specifically, the glucocorticoid
receptor. The present invention also provides pharmaceutical compositions
containing these compounds and methods for using these compounds to treat
animals requiring glucocorticoid receptor agonist or antagonist therapy.
Glucocorticoid receptor modulators are useful to treat diseases, such as
obesity, diabetes, inflammation and others as described below. The present
invention also provides processes for preparing these compounds
##STR1##
A invenção atual fornece compostos non-non-steroidal da fórmula I, including os prodrugs e pharmaceutically os sais aceitáveis disso, que são moduladores seletivos (por exemplo, agonists, agonists parciais e antagonistas) de um receptor steroid, especificamente, o receptor glucocorticoid. A invenção atual fornece também as composições pharmaceutical que contêm estes compostos e métodos usando estes compostos tratar os animais que requerem o agonist glucocorticoid do receptor ou a terapia do antagonista. Os moduladores glucocorticoid do receptor são úteis tratar doenças, tais como o obesity, o diabetes, o inflammation e o outro como descritas abaixo. A invenção atual fornece também processos preparando estes o ## do ## STR1 dos compostos
