Endothelial dysfunction is a known indicator of coronary artery disease.
Endothelial dysfunction is detected by measuring presence of a marker in
arteries following the release of blood flow into the limb after a period
of blockage of blood flow into the limb. The blood flow is measured in a
pair of laterally opposed limbs, such as the patient's forearms, and the
marker presence is compared between both limbs. One efficient marker is a
tracer containing a radionuclide and the non-invasive measurement of the
radionuclide is carried out by gamma ray detection.
