Pyrimidine derivatives for inhibition of cell proliferation

   
   

Compounds of the formula (I): wherein Ring A, R.sup.1, R.sup.3, R.sup.4, p, q, and n are as defined within and a pharmaceutically acceptable salts and in vivo hydrolyzable esters are described. Also described are processes for their preparation and their use as medicaments, particularly medicaments for producing a cell cycle inhibitory (anti-cell-proliferation) effect in a warm-quest-blooded animal, such as man. ##STR1##

Compostos da fórmula (i): wherein o anel A, R.sup.1, R.sup.3, R.sup.4, p, q, e n é como definido dentro e os sais pharmaceutically aceitáveis e em esters hydrolyzable de vivo são descritos. São descritos também os processos para sua preparação e seu uso como os medicaments, particularmente medicaments para produzir um efeito inhibitory do ciclo da pilha (anti-pilha-anti-cell-proliferation) em um animal do morno-warm-quest-blooded-blooded, tal como o homem. ## do ## STR1

 
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