A polypeptide suitable for use in vaccination against Streptococcal
infections comprises: a) the amino acid sequence of SEQ ID No 1; b) a
variant of (a) which is capable of binding an anti-MtsA antibody; or (c) a
fragment of (a) or (b) of at least 6 amino acids in length which is
capable of binding an anti-MtsA antibody. A vaccine composition comprises:
a) the amino acid sequence of SEQ ID No 1; b) a variant of (a) which is
capable of generating an immune response to a Streptococcal; or (c) a
fragment of (a) or (b) of at least 6 amino acids in length which is
capable of generating an immune response against a Streptococcus.
