Pharmaceutical composition that exhibits reduced side-effects comprising O-(3-piperidino-2-hydroxy-1-propyl)nicotinic acid amidoxime and a pyrimidine derivative with known antitumor activity

   
   

Pharmaceutical compositions that exhibit reduced gastrointestinal side-effects comprising a known active substance having antitumor effects selected from the group consisting of pyrimidine derivatives, or a pharmaceutically acceptable acid addition salt thereof, and O-(3-piperidino-2-hydroxy-1-propyl)nicotinic acid amidoxime, or a pharmaceutically acceptable acid addition salt thereof, are disclosed.

Des compositions pharmaceutiques qui montrent des effets secondaires gastro-intestinaux réduits comportant une substance active connue ayant des effets antitumoraux choisis dans le groupe les dérivés de pyrimidine, ou un sel pharmaceutiquement acceptable d'addition acide en, et amidoxime acide d'O-(3-piperidino-2-hydroxy-1-propyl)nicotinic, ou un sel pharmaceutiquement acceptable d'addition acide en, sont révélés.

 
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