Sulfonamide and sulfamide substituted imidazoquinolines and methods for the treatment of periodontal disease using these and other immune response modifiers

   
   

The disclosure provides methods for the treatment and prevention of periodontal disease. In preferred embodiments, the invention provides for local treatment of periodontal tissues with a pharmaceutical composition including an immune response modifier (IRM) selected from the group of immune response modifiers comprising imidazoquinoline amines, imidazopyridine amines, 6,7-fused cycloalkylimidazopyridine amines, imidazonaphthyridine amines, oxazoloquinoline amines, thiazoloquinoline amines and 1,2-bridged imidazoquinoline amines.

De onthulling verstrekt methodes voor de behandeling en de preventie van periodontal ziekte. In aangewezen belichamingen, voorziet de uitvinding lokale behandeling van periodontal weefsels met een farmaceutische samenstelling met inbegrip van een immune reactiebepaling (IRM) die uit de groep immune reactiebepalingen bestaand wordt geselecteerd imidazoquinoline uit aminen, imidazopyridineaminen, 6.7-gesmolten cycloalkylimidazopyridineaminen, imidazonaphthyridineaminen, oxazoloquinolineaminen, thiazoloquinolineaminen en 1.2-overbrugde imidazoquinolineaminen.

 
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