Human bad polypeptides, encoding nucleic acids and methods of use

   
   

The invention provides an isolated gene and an isolated nucleic acid sequence encoding human Bad and functional fragments thereof. Also provided is an isolated human Bad polypeptide and functional fragments thereof. Methods of identifying human Bad binding partners and methods of screening for compounds which interfere with the association of human Bad interacting polypeptides with human Bad are also provided. Finally, methods for decreasing or increasing the viability of a cell are provided as well.

A invenção fornece um gene isolado e uma seqüência isolada do ácido nucleic que codificam fragmentos maus e funcionais humanos disso. São fornecidos também um polypeptide mau humano isolado e uns fragmentos funcionais disso. Os métodos de identificar sócios obrigatórios maus humanos e os métodos de selecionar para os compostos que interferem com a associação de polypeptides de interação maus humanos com bad humano são fornecidos também. Finalmente, os métodos para diminuir ou aumentar o viability de uma pilha são fornecidos também.

 
Web www.patentalert.com

< Antibody that specifically binds an Mch4 polypeptide

< Treatment of inflammation-associated disorders using interleukin-1.beta.-converting enzyme (ICE)/CED-3 family inhibitors

> Membrane derived caspase-3, compositions comprising the same and methods of use therefor

> Antibody that specifically binds an Mch5 polypeptide

~ 00147