Removal of dye-labeled dideoxy terminators from DNA sequencing reactions

   
   

This invention provides methods for removing unincorporated dye-labeled molecules from a mixture that includes dye-labeled polynucleotides or other polymers and the unincorporated dye-labeled molecules. The methods involve adsorbing the unincorporated dye-labeled molecules into a plurality of particles that are made up of one or more porous hydrophobic materials that are encapsulated in a hydrophilic matrix.

Questa invenzione fornisce i metodi per la rimozione unincorporated le molecole ting-identificate da una miscela che include i polynucleotides ting-identificati o altri polimeri ed unincorporated le molecole ting-identificate. I metodi coinvolgono l'adsorbimento unincorporated le molecole ting-identificate in una pluralità di particelle che si compongono di uno o più materiali idrofobi porosi che sono incapsulati in una tabella idrofila.

 
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