Azaheterocyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene as 5-HT1A antagonists

   
   

Compounds of the formula ##STR1## are useful for treating the cognitive deficits due to aging, stroke, head trauma, Alzheimer's disease or other neurodegenerative diseases, or schizophrenia. The compounds of the invention are also useful for the treatment of disorders such as anxiety, aggression and stress, and for the control of various physiological phenomena, such as appetite, thermoregulation, sleep and sexual behavior.

De samenstellingen van de formule ## STR1 ## zijn nuttig om de cognitieve tekorten te behandelen toe te schrijven aan het verouderen, slag, hoofdtrauma, de ziekte van Alzheimer of andere neurodegenerative ziekten, of schizofrenie. De samenstellingen van de uitvinding zijn ook nuttig voor de behandeling van wanorde zoals bezorgdheid, agressie en spanning, en voor de controle van diverse fysiologische fenomenen, zoals eetlust, warmteregeling, slaap en seksueel gedrag.

 
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> Azabicyclylmethyl derivatives of 7,8-dihydro-1,6,9-trioxa-3-aza-cyclopenta[a]naphthalene as 5-ht1a antagonists

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