Thiol-based NAALADase inhibitors

   
   

This invention relates to new compounds, pharmaceutical compositions and diagnostic kits comprising such compounds, and methods of using such compounds for inhibiting NAALADase enzyme activity, detecting diseases where NAALADase levels are altered, effecting neuronal activity, effecting TGF-.beta. activity, inhibiting angiogenesis, and treating glutamate abnormalities, diabetic neuropathy, pain, compulsive disorders, prostate diseases, cancers and glaucoma.

 
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< Anti-inflammatory peptides derived from IL-2 and analogues thereof

< Modified vitamin K-dependent polypeptides

> Phenylethynyl and styryl derivatives of imidazole and fused ring heterocycles

> Methods and compounds for inhibiting -amyloid peptide release and/or its synthesis

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