Cyano-substituted dihydropyrimidine compounds and their use to treat diseases

   
   

The present invention provides compounds of formula I ##STR1## and pharmaceutically acceptable salts thereof. The formula I compounds induce mitotic arrest thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases which can be treated by inducing mitotic arrest.

La presente invenzione fornisce i residui del ## del ## STR1 di formula I e farmaceuticamente dei sali accettabili di ciĆ². I residui di formula I inducono l'arresto mitotic quindi che li rende utili come agenti anticancro. I residui di formula I sono inoltre utili per il trattamento di altre malattie che possono essere trattate inducendo l'arresto mitotic.

 
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