Methods and compositions for detecting signals in binding assays using microparticles

   
   

Methods and compounds are provided for detecting target molecules in a sample using specific binding assays. In particular, methods are provided for detecting a nucleic acid target in a sample. In one embodiment, the presently claimed invention provides a method of labeling a hybridized target wherein the target comprises a binding ligand. In another embodiment, the presently claimed invention provides methods of signal amplification.

 
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> Expression monitoring by hybridization to high density oligonucleotide arrays

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