Lentiviral-mediated growth factor gene therapy for neurodegenerative diseases

   
   

Disclosed and claimed are methods for treating or preventing neurodegenerative diseases, conditions or maladies or symptoms or physiology associated therewith, such as treating or preventing Parkinson's disease or symptoms or physiology associated therewith such as motor deficits or nigrostriatal degeneration; or, for inducing nigrostriatal regeneration. Advantageously, the methods involve administering a lentiviral vector that expresses GDNF, such as human GDNF, or a variant, homolog, analog or derivative thereof.

Se divulgan y demandado los métodos para tratar o prevenir las enfermedades, las condiciones o los maladies o los síntomas o fisiología neurodegenerative asociados therewith, por ejemplo tratar o la prevención de la enfermedad de Parkinson o los síntomas o fisiología asociados therewith por ejemplo déficit del motor o la degeneración nigrostriatal; o, para inducir la regeneración nigrostriatal. Ventajoso, los métodos implican el administrar de un vector lentiviral que exprese GDNF, tal como GDNF humano, o un variable, homólogo, análogo o derivado de eso.

 
Web www.patentalert.com

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