Use of .DELTA.5-androstene-3.beta.-OL7,17-dione in the treatment of arthritis

   
   

Arthritis can be treated by administering therapeutic amounts of .DELTA.5-androstene-3.beta.-ol-7,17-dione and metabolizable precursors thereof, such a .DELTA.5-androstene-3.beta.-acetoxy-7,17-dione, which are readily metabolized in vivo to .DELTA.5-androstene-3.beta.-ol-7,17-dione but are not appreciably metabolizable in vivo to androgens, estrogens or dehydroepiandrosterone. Such treatment can be prophylactic, ameliorative or curative in nature.

Артрит может быть обработан путем administering терапевтическое количество DELTA.5-androstene-3.beta.-ol-7,17-dione и metabolizable прекурсоров thereof, такое DELTA.5-androstene-3.beta.-acetoxy-7,17-dione, которые готово метаболизированы в vivo к DELTA.5-androstene-3.beta.-ol-7,17-dione но не appreciably metabolizable в vivo к андрогенам, эстрогенам или dehydroepiandrosterone. Такая обработка может быть prophylactic, ameliorative или curative по сути.

 
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