The present invention relates to compounds capable of acting as androgen
receptor antagonists, pharmaceutical formulations containing the same, and
methods of use thereof. Such uses include, but are not limited to, use as
antitumor agents, particularly for the treatment of cancers such as colon,
skin and prostate cancer and to induce androgen receptor antagonist
activity in a subject afflicted with an androgen-related affliction.
Examples of androgen-related afflictions include, but are not limited to,
baldness, hirsutism, behavioral disorders, acne, and uninhibited
spermatogenesis wherein inhibition of spermatogenesis is so desired.
