The present invention relates to compounds and derivatives thereof, their
synthesis, and their use as integrin receptor antagonists. More
particularly, the compounds of the present invention are antagonists of
the integrin receptors .alpha.v.beta.3, .alpha.v.beta.5, and/or
.alpha.v.beta.6 and are useful for inhibiting bone resorption, treating
and preventing osteoporosis, and inhibiting vascular restenosis, diabetic
retinopathy, macular degeneration, angiogenesis, atherosclerosis,
inflammation, wound healing, viral disease, tumor growth, and metastasis.
