Method for producing optically active mandelic acid derivatives

   
   

The present invention provides a method for enzymatically producing optically active mandelic acid derivatives. An optically active mandelic acid derivative (shown as Formula II) is produced by reacting a culture or cell body of a microorganism, or processed products thereof, with a phenylglyoxylic acid derivative, and then recovering the obtained optically active mandelic acid derivative, wherein the microorganism has the ability to stereo-selectively reduce the phenylglyoxylic acid derivative. An optically active mandelic acid obtained according to the present invention is useful as an intermediate for the synthesis of pharmaceuticals and agricultural chemicals. ##STR1##

La presente invenzione fornisce un metodo per enzimaticamente produrre otticamente i derivati acidi mandelici attivi. Un derivato acido mandelico otticamente attivo (indicato come formula Ii) è prodotto dalla reazione dadel corpo delle cellule o della coltura di un microorganismo, o dai prodotti proceduti di ciò, con un derivato acido phenylglyoxylic ed allora recuperare il derivato acido mandelico attivo otticamente ottenuto, in cui il microorganismo fa ridurre l'abilità a stereo-selettiv'il derivato acido phenylglyoxylic. Un acido mandelico otticamente attivo ottenuto secondo la presente invenzione è utile come intermediario per la sintesi dei prodotti farmaceutici e dei prodotti chimici agricoli. ## del ## STR1

 
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