Process for preparing 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)eth yl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide

   
   

A method for preparing 5-(4-fluorophenyl)-1-[2-((2R,4R)4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-eth yl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide (I), a key intermediate in the synthesis of atorvastatin calcium, is described. ##STR1##

Une méthode pour préparer 5-(4-fluorophenyl)-1-[2-((2R, l'4R)4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-eth phenylamide acide de yl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic (i), une intermédiaire de clef dans la synthèse du calcium d'atorvastatin, est décrite. ## du ## STR1

 
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