Transmucosal delivery system

   
   

A device for delivering a heparinic anticoagulant across a mucosal surface in order to achieve or maintain a therapeutically effective blood level of the heparinic anticoagulant. The device involves a matrix containing a therapeutically effective amount of a heparinic anticoagulant, and a mucoadhesive or other mechanism for maintaining the matrix in contact with the mucosal surface for a time sufficient to allow release of the heparinic anticoagulant to the mucosal surface.

Um dispositivo para entregar um anticoagulante heparinic através de uma superfície mucosal a fim conseguir ou manter um nível therapeutically eficaz do sangue do anticoagulante heparinic. O dispositivo envolve uma matriz que contêm uma quantidade therapeutically eficaz de um anticoagulante heparinic, e um mecanismo mucoadhesive ou outro para manter a matriz no contato com a superfície mucosal por um momento suficiente permitir a liberação do anticoagulante heparinic à superfície mucosal.

 
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> Mucoadhesive compositions for administration of biologically active agents to animal tissue

> Polymeric bioadhesive emulsions and suspensions and methods of treatment

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