Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction

   
   

Methods of using inhibitors of the CD2/LFA-3 interaction in treating skin conditions characterized by increased T cell activation and abnormal antigen presentation in the dermis and epidermis in mammals, including humans. Such conditions include psoriasis, UV damage, e.g., photoaging, atopic dermatitis, cutaneous T cell lymphoma such as mycosis fungoides, allergic and irritant contact dermatitis, lichen planus, alopecia areata, pyoderma gangrenosum, vitiligo, ocular cicatricial pemphigoid, and urticaria.

Métodos de usar los inhibidores de la interacción CD2/LFA-3 en las condiciones de la piel que tratan caracterizadas por la activación creciente de la célula de T y la presentación anormal del antígeno en el dermis y la epidermis en mamíferos, incluyendo seres humanos. Tales condiciones incluyen el psoriasis, daños UV, e.g., el photoaging, dermatitis atópico, linfoma cutáneo de la célula de T tal como fungoides de la micosis, dermatitis de contacto alérgico e irritante, planus del liquen, areata de la alopecia, gangrenosum de la piodermia, vitiligo, pemphigoid cicatricial ocular, y urticaria.

 
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