System and apparatus for nucleic acid sequencing of single molecules by polymerase synthesis

   
   

This invention relates to improved methods for sequencing and genotyping nucleic acid in a single molecule configuration. The method involves single molecule detection of fluorescent labeled PPi moieties released from NTPs as a polymerase extension product is created.

Deze uitvinding heeft op betere methodes om nucleic zuur in één enkele moleculeconfiguratie te rangschikken en genotyping betrekking. De methode houdt enige moleculeopsporing van fluorescente geëtiketteerde delen PPi in die van NTPs worden vrijgegeven aangezien een product van de polymeraseuitbreiding wordt gecreeerd.

 
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