5-pyrimidinecarboxamide derivatives and the pharmaceutical compositions containing said derivatives

   
   

The present invention relates to novel 5-pyrimidinecarboxamide derivatives and the pharmaceutical compositions containing said derivatives, and more specifically, to 5-pyrimidinecarboxamide derivatives and their pharmacutically able salts, the process for preparing them, and the pharmaceutical compositions containing said compounds as active ingredients. In particular, said 5-pyrimidinecarboxamide derivatives of the present invention, due to their inhibitory activity against the proliferation of human immunodeficiency virus (HIV) as well as hepatitis B virus (HBV), can be used as a therapeutic agent as well as a preventive agent for hepatitis B and acquired immune deficiency syndrome (AIDS).

A invenção atual relaciona-se aos derivatives da novela 5-pyrimidinecarboxamide e as composições pharmaceutical que contêm derivatives ditos, e mais especificamente, aos derivatives 5-pyrimidinecarboxamide e seus sais pharmacutically capazes, o processo para prepará-los, e as composições pharmaceutical que contêm compostos ditos como ingredientes ativos. Em particular, disse os derivatives 5-pyrimidinecarboxamide da invenção atual, devido a sua atividade inhibitory de encontro ao proliferation do vírus humano do immunodeficiency (HIV) as.well.as o vírus do hepatitis B (HBV), pode ser usado como um agente therapeutic as.well.as um agente preventivo para o hepatitis B e o syndrome imune adquirido da deficiência (AIDS).

 
Web www.patentalert.com

< -modified nucleoside triphosphates

< 2-amino-9H-purin-9-yl compounds and methods for inhibiting/treating HIV infections and AIDS related symptoms

> Methods for treatment of HIV and other infections using a T cell or viral activator and anti-retroviral combination therapy

> Agents that modulate DNA-PK activity and methods of use thereof

~ 00119