Enzymes for the detection of specific nucleic acid sequences

   
   

The present invention relates to novel enzymes designed for direct detection, characterization and quantitation of nucleic acids, particularly RNA. The present invention provides enzymes that recognize specific nucleic acid cleavage structures formed on a target RNA sequence and that cleave the nucleic acid cleavage structure in a site-specific manner to produce non-target cleavage products. The present invention provides enzymes having an improved ability to specifically cleave a DNA member of a complex comprising DNA and RNA nucleic acid strands.

A invenção atual relaciona-se aos enzymes da novela projetados para a deteção, a caracterização e o quantitation diretos de ácidos nucleic, particularmente RNA. A invenção atual fornece os enzymes que reconhecem as estruturas específicas do cleavage do ácido nucleic dadas forma em uma seqüência do RNA do alvo e que cleave a estrutura do cleavage do ácido nucleic em uma maneira local-específica para produzir produtos do cleavage do non-alvo. A invenção atual fornece os enzymes que têm uma abilidade melhorada de cleave especificamente um membro do DNA costas de um ácido nucleic compreendendo complexo do DNA e do RNA.

 
Web www.patentalert.com

< Substituted diphenyl heterocycles useful for treating HCV infection

< Single-chain multiple antigen-binding molecule, its preparation and use

> 14189, a novel human kinase and uses thereof

> Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for caspases and other enzymes and the use thereof

~ 00119