Single-chain multiple antigen-binding molecule, its preparation and use

   
   

The present invention relates to a single-chain, multiple antigen-binding molecule with diverse variable domains of a heavy and of a light chain of an immunoglobulin, which are connected in the form of a VH-VL construct, which are in turn connected together via a peptide, and to the preparation and use thereof as pharmaceutical or diagnostic aid.

La presente invenzione riguarda una molecola antigene-legantesi a catena semplice e multipla con i dominii variabili vari di di un chain pesante e chiaro di un'immunoglobulina, che sono collegati sotto forma d'una costruzione di VH-VL, che a loro volta sono collegati insieme via un peptide ed alla preparazione ed all'uso di ciĆ² come sussidio farmaceutico o diagnostico.

 
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