Guanosine triphosphate (GTP) binding protein-coupled receptor proteins

   
   

The present invention has provided a human-derived novel G protein-coupled receptor protein expressed in the brain, rat-derived protein corresponding to it, and their genes. Use of the receptors makes it possible to screen their ligands and compounds that are candidates for medicines. These ligands and candidate compounds would be useful in the diagnosis and treatment of diseases arising from disorders of signal transduction pathway mediated by the G protein-coupled receptor of the invention.

La actual invención ha proporcionado una proteína protei'na-juntada G humano-derivada del receptor de la novela expresada en el cerebro, la proteína rata-derivada que correspondía a ella, y sus genes. El uso de los receptores permite defender sus ligands y los compuestos que son candidatos a medicinas. Estos ligands y compuestos del candidato serían útiles en la diagnosis y el tratamiento de las enfermedades que se presentaban de desórdenes del camino del transduction de la señal mediado por el G protei'na-junto' el receptor de la invención.

 
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