A closure device is provided for sealing a puncture in a body vessel. The
closure device includes an energy delivery device for delivering energy to
tissue adjacent the vessel puncture which enhances an adhesiveness of the
tissue to a closure composition precursor. The closure device includes a
sealer/dilator for dilating tissue adjacent a vessel puncture, at least
one closure composition precursor lumen within The sealer/dilator having
an entrance part adjacent the proximal end of the sealer/dilator through
which one or more fluent closure composition precursors can be delivered
into the closure composition precursor lumen and an exit port adjacent the
distal end of the sealer/dilator through which the one or more fluent
closure composition precursors can be delivered outside the vessel
adjacent the vessel puncture, and a plugging catheter for positioning
within the vessel puncture, the plugging catheter extending distally from
the sealer/dilator and including at least one position sensing mechanism
such that the exit port of the closure composition precursor lumen is
outside the vessel when the at least one position sensing mechanism is
detected outside the vessel.
